No serious renal events were reported. Among a complete of 16,863 measurements of serum creatinine, amounts above the upper limit of the normal range were uncommon, and 99 percent of the ideals were 1. All adverse events and serious adverse events are shown in Tables 4 and 5 in the Supplementary Appendix. Debate The results of our study showed that in premenopausal women with early breast cancer, treatment with anastrozole and treatment with tamoxifen were associated with equivalent rates of disease-free survival. The addition of zoledronic acid to adjuvant endocrine therapy improved the rate of disease-free survival, as compared with endocrine therapy by itself. At a median follow-up of 47.8 months, 821 of 904 sufferers who received endocrine therapy alone had been free from disease, and 878 of 904 patients had been alive; in the cohort of sufferers who received zoledronic acid, 845 of 899 individuals were disease-free and 883 of 899 were alive.Schaller, whose singular objective is to raise awareness about cystic fibrosis, has made an appearance in Forbes magazine, THE BRAND NEW York Times on the web and was voted the 2009 2009 Applebee’s National Genuine Hero. She’ll travel through 14 metropolitan areas and seven states, including Illinois, Iowa, Nebraska, Colorado, Utah, Nevada, and California. Related StoriesSensiQ Technology and Inventiva create a European Center of Excellence in surface area plasmon resonance technologiesAlport syndrome: an interview with Dr Paul Grint, CMO, RegulusGenetic carrier screening: an interview with Don Hardison, CEO of Good Start GeneticsCystic fibrosis is a fatal, genetic disease that clogs the lungs with thick mucus, causing life-threatening infections and premature death.