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Advancing knowledge of diet-gene interactions Nutrigenomics experts worldwide have aligned.
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Advancing knowledge of diet-gene interactions Nutrigenomics experts worldwide have aligned.

Related StoriesImproved gene therapy treatment shows promise in mice with cystic fibrosisApoE4-carrying males with Alzheimer's disease at risk of brain bleedsDiet missing soluble fiber promotes swelling in the intestines, resulting in weight gain Advancing our knowledge of diet-gene interactions is critical, says Ordovas, who is also a professor in the Friedman School of Nutrition Policy and Science in Tufts, but knowledge alone is not sufficient for us to effectively address wellness disparities and fight chronic disease across the world. He emphasizes that scientists must collaborate with scholars and policy makers, as well.Families A and B got novel frameshift mutation variants in MKRN3 . We then examined exome data from the additional 25 users of the other 12 family members in the analysis and found another novel frameshift mutation in MKRN3 in Households D and E. A novel missense variant was identified in Family C .0 and a Protein Analysis through Evolutionary Romantic relationship rating of 0.95 for the probability of being deleterious. We confirmed all variants by using Sanger sequencing and tested for cosegregation between the variant and central precocious puberty in an additional 8 associates from Families A through E who didn’t undergo exome sequencing.