Cammann, Annahita Sarcon, M.D., Verena Geyer, Catharina A. Neumann, Burkhardt Seifert, Ph.D., Jens Hellermann, M.D., Moritz Schwyzer, M.D., Katharina Eisenhardt, M.D., Josef Jenewein, M.D., Jennifer Franke, M.D., Hugo A. Katus, M.D., Christof Burgdorf, M.D., Heribert Schunkert, M.D., Christian Moeller, M.D., Holger Thiele, M.D., Johann Bauersachs, M.D.D., Heinz-Peter Schultheiss, M.D., Charles A. Laney, M.D., Lawrence Rajan, M.D., Guido Michels, M.D., Roman Pfister, M.D., Christian Ukena, M.D.D., Raimund Erbel, M.D., Alessandro Cuneo, M.D., Karl-Heinz Kuck, M.D., Claudius Jacobshagen, M.D., Gerd Hasenfuss, M.D., Mahir Karakas, M.D., Wolfgang Koenig, M.D., Wolfgang Rottbauer, M.D., Samir M.Glutamine supplementation as compared with no glutamine didn’t have a significant effect on the outcomes of organ failure or infections . Antioxidant supplementation as compared with no antioxidants didn’t have a significant effect on any secondary outcome . Adverse Events A complete of 52 significant adverse events were reported in 46 patients; 4 were considered to be related to study supplements potentially. There were no significant variations in rates of significant adverse events across organizations . The rate of recurrence of high urea amounts was higher among sufferers who received glutamine than among those who didn’t . Laboratory Substudy Baseline median plasma glutamine and selenium amounts were within normal limits in 66 substudy sufferers .