Changing Incidence of Pump Thrombosis The occurrence of confirmed pump thrombosis increased steeply after approximately March 2011, from 2.2 percent at three months after implantation to 8.4 percent by January 2013 . A similar pattern was observed at all three establishments and for multiple surgeons . The median time from implantation to confirmed pump thrombosis reduced from 18.6 months before March 2011 to 2.7 months after and during March 2011. What had been a constant risk of confirmed pump thrombosis of 0.4 percent per month after implantation developed into an early hazard that peaked at 2 months and fell to a sustained 0.6 percent monthly ; this risk was consistent across institutions . This pattern of alter in the incidence of verified pump thrombosis also characterized the price of confirmed plus suspected events .Dr. Stefan, who received his doctoral level in Genetics from University of Bucharest, Romania, in 2000, will study the Role of interferon alpha in advancement of AITD: Epigenetic regulation of crucial genes. In autoimmune thyroid diseases , in which a person’s own disease fighting capability episodes and damages the thyroid gland, individuals with certain genetic variants are predisposed to develop AITD when exposed to associated environmental elements. Dr. Stefan proposes to identify the epigenetic mechanisms that mediate these gene/environment interactions by learning changes in gene expression triggered by interferon that bring about AITD.